SYNLAB Italy
Senior Researcher, SYNLAB IRCCS SDN, Naples
The lncRNA TEX41 is upregulated in pediatric B-Cells Acute Lymphoblastic Leukemia and it is necessary for leukemic cell growth
Biomarker Research – https://doi.org/10.1186/s40364-021-00307-7
What inspired your research and what did it cover?
My research work was inspired by the need to identify a disease in the best possible way, especially when it comes to pediatric oncological diseases. In fact, my research focuses on the identification of new diagnostic biomarkers of pediatric acute leukemia. Especially with pediatric tumors, correctly and promptly identifying the disease is essential to ensuring targeted and above all effective therapy.
Which aspect(s) of your research work are you particularly excited about?
Obviously, the whole research process made me particularly excited. But the fact of having identified a molecule so simple to detect which, if silenced, could have a therapeutic role, makes me overexcited about our research. In fact, there are not many molecules that can be used simultaneously for diagnostic and therapeutic purposes in pediatric leukemias. Having identified one makes us particularly proud of our work.
Looking at the potential of your findings, what difference can they make?
Increasing the quality of biomarkers that are useful in the identification of a disease is a fundamental goal of medical science. Our results have allowed us to identify a new long non-coding RNA that is able to discriminate between the various types of pediatric leukemia and guarantee a correct evaluation of the therapeutic path. Furthermore, being easy to detect, this new biomarker could be used to improve the clinical management of patients, to develop innovative diagnostic protocols for personalized medicine.
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